RUTHENIUM CHLORIDE OXIDE, AMMONIATE
ruthenium red
CAS: 11103-72-3
Molecular Formula: Cl6H42N14O2Ru3
RUTHENIUM CHLORIDE OXIDE, AMMONIATE - Names and Identifiers
| Name | ruthenium red |
| Synonyms | RR RUTHENIUM RED ruthenium red RUTHENIUM SALT Ruthenium Red test solution(ChP) RUTHENIUM OXYCHLORIDE AMMONIATED Ammoniated ruthenium oxychloride RUTHENIUM CHLORIDE OXIDE, AMMONIATE RUTHENIUM TETRAMMINOHYDROXYCHLOROCHLORIDE RUTHENIUM (III) CHLORIDE OXIDE, AMMONIATED |
| CAS | 11103-72-3 |
| EINECS | 802-133-7 |
| InChI | InChI=1/6ClH.14H3N.2H2O.3Ru/h6*1H;14*1H3;2*1H2;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6 |
| InChIKey | ZXYSDUPLHOJIOR-UHFFFAOYSA-H |
RUTHENIUM CHLORIDE OXIDE, AMMONIATE - Physico-chemical Properties
| Molecular Formula | Cl6H42N14O2Ru3 |
| Molar Mass | 786.35 |
| Density | 3.110 |
| Melting Point | >500°C |
| Water Solubility | Soluble in water and ammonium hydroxide. |
| Solubility | Soluble in water, ammonia, also soluble in potassium chloride solution and alum solution, insoluble in ethanol, glycerin and clove oil |
| Appearance | Reddish brown powder |
| Specific Gravity | 3.11 |
| Color | Red |
| Merck | 14,8300 |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Stability | Stable. |
| MDL | MFCD00011479 |
| Use | This product is for scientific research only and shall not be used for other purposes. |
| In vitro study | Ruthenium red staining of intracellular organelles and structures seemed to depend on the time of exposure to this agent, as well on the concentration used. Ruthenium red efficiently blocks the L-type calcium current in a dose-dependent manner in in guinea-pig isolated ventricular heart cells, with EC 50 of 0.8 μM. Ruthenium red (10 μM) blocks the sarcoplasmic Ca release channels or the mitochondrial Ca uptake, and blocks 26.7 % of the sodium current, and slowed its inactivation time-course in guinea-pig isolated ventricular heart cells. |
RUTHENIUM CHLORIDE OXIDE, AMMONIATE - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| RTECS | VM2656500 |
| HS Code | 28439000 |
RUTHENIUM CHLORIDE OXIDE, AMMONIATE - Reference
| Reference Show more | 1. Chen Zhongquan, Fu Chunru, Fu Fengqin, et al. Effects of piperine on arecoline's promotion of isolated small intestinal smooth muscle movement in rabbits [J]. World Chinese Journal of Digestion, 2019, 27(01):20-28. 2. Wang Yue, Li Kaikai, li chunmei. the effect of pectin and tannin interaction on astringency of different persimmon varieties during ripening [J]. modern food science and technology, 2019, v.35;No.237(05):93-100. |
RUTHENIUM CHLORIDE OXIDE, AMMONIATE - Introduction
Gum, gum, animal tissue and bacterial staining.
Last Update：2022-10-16 17:12:05
RUTHENIUM CHLORIDE OXIDE, AMMONIATE - Reference Information
| color index | 77800 |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| biological activity | Ruthenium red (Ammoniated ruthenium oxychloride) is a polycation dye, widely used in the observation of cells, tissues and vegetative bacteria under electron microscope (EM). Ruthenium red can react strongly with phospholipids and fatty acids and bind with acidic mucopolysaccharides. Ruthenium red is also an L-type calcium current (ICa) blocker. |
| target | I Ca |
| use | interacts with calcium ion-bound proteins to inhibit mitochondrial Ca2 + unidirectional transporter (uniporter); Capsicum capsaicin antagonist; Blocking VR1 vanillin receptor coupled ion channel. Ruthenium red (36%) can also be used as a colorant for electron microscopy histology, used with glutaraldehyde for mucopolysaccharide staining, and used with osmium tetroxide to increase contrast. During the embedding procedure, it is used to maintain wintersweet of pathogenic bacteria. The product is also reported to be used for capsular coloration of the cholera solitary bacteria. |
Last Update：2024-04-10 22:29:15
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